The mean MIH of Impella heart pumps is about 5, well below the MIH upper limit of 20 for use of blood pumps in clinical setting.

Circulation.

A three-year, investigator-led, prospective study of Japanese patients who received an Impella heart pump finds use of Impella is associated with a … 2017. https://www.heart.org/-/media/files/get-involved/advocacy/burden-report-consumer-report.pdf?la=en&hash=0A2A75E9FE82F7BEAE6A6A0FDB64E3FCE2BD86699. Rehospitalizations among patients in the Medicare fee-for-service program.

2012;126:1717-1727. doi: 10.1161/CIRCULATIONAHA.112.09819410. Impella demonstrates reduced LOS.8.

CRF is committed to igniting the next wave of innovation in research and education that will help doctors save and improve the quality of their patients’ lives.

The Impella heart pump is manufactured by Abiomed (NASDAQ: ABMD) and is the most studied mechanical circulatory support device in the history of the U.S. FDA with more than 14 years of FDA studies, real-world clinical data on more than 125,000 patients, and more than 650 peer-reviewed publications.

The data, from a robust body of US and European evidence from 2004 – 2019, includes the […] Gregory D, Scotti DJ.

Jencks SF, Williams MV, Coleman EA.

Cost savings for pVAD compared to ECMO in the management of acute myocardial infarction complicated by cardiogenic shock: an episode-of-care analysis.

A prospective, randomized clinical trial of hemodynamic support with Impella 2.5 versus intra-aortic balloon pump in patients undergoing high-risk percutaneous coronary intervention: the PROTECT II study.

Utilization and outcomes of Impella vs IABP among patients with AMI complicated by cardiogenic shock undergoing PCI. By Dominick J. Angiolillo, MD, PhD, and Francesco Franchi, MDRenal Protection During Impella®-Supported PCI in Patients With High-Risk Complex Coronary Artery Disease3.

J Manag Care Med. Am Health Drug Benefits.

To mark the five year anniversary of the study by Stretch, et al., on cost and outcomes trends for short-term mechanical circulatory support, Abiomed announces a comprehensive publication review of cost and comparative effectiveness of Impella in high-risk PCI and cardiogenic shock. Poster presented at the Society for Cardiovascular Angiography & Interventions (SCAI) 2019 Scientific Sessions; May 19-22; Las Vegas, Nevada.With S. Jay Mathews, MD, MS, FACC; Chris Metzger, MD; Waqas R. Qureshi, MD, MS; Jawairia Sahar K. Mirza, MBBS; Gus Theodos, MD, FACC, FSCAI; Brian Kolski, MD; and Suhail Dohad, MD, FACC2.

CONCLUSIONS: On the basis of evidence of low to very low quality, Impella 2.5 devices were associated with improved hemodynamic stability, but had mortality rates and safety profile similar to IABPs in high-risk PCI and cardiogenic shock. Gregory D, Scotti DJ, de Lissovoy G, et al.

Presented at: AHA 2019.

MIH is calculated from the slope of the PFH concentration versus time plot.

Impella heart pumps are tested in vitro using mock circulation loop using porcine blood maintained at 37⁰C for 3-6 hours. With a negative, or dominant, ICER of -$134,932/life-year gained, Impella therapy not only improved outcomes but resulted in a cost savings in acute myocardial infarction patients with cardiogenic shock in this study. 2013;16:61-69.Clinical Implications and Treatment of Coronary Microvascular Obstruction in STEMIEvolving Evidence for Protected PCI With Impella® to Treat High-Risk Complex CAD PatientsIt is possible that new, minimally invasive technologies, such as the Impella pVAD, can provide the opportunity to concomitantly improve clinical outcomes, quality of care, and shared savings opportunities for patients and providers.

2014;83:E183-E192.

incidence, outcomes and cost analysis. 6 Maini B, Gregory D, Scotti DJ, Buyantseva L. Percutaneous cardiac assist devices compared with surgical hemody-namic support alternatives: cost-effectiveness in the emergent setting. Catheter Cardiovasc Interv. ABOUT IMPELLA HEART PUMPS

The Impella 5.0 heart pump is an intravascular microaxial blood pump that delivers up to 5.0 L/min of forward flow blood from the left ventricle to the aorta. Cost-effectiveness and Clinical Outcomes of Impella Hemodynamic Support Compared with Intra- Aortic Balloon Pump in High Risk Patients Receiving PCI: Results from the PROTECT II …

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